Cast & Crew
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| [1] | Johnny Galecki | ... | Leonard Hofstadter (125 episodes, 2007-2013) |
| [2] | Jim Parsons | ... | Sheldon Cooper (125 episodes, 2007-2013) |
| [3] | Kaley Cuoco | ... | Penny (124 episodes, 2007-2013) |
| [4] | Simon Helberg | ... | Howard Wolowitz (124 episodes, 2007-2013) |
| [5] | Kunal Nayyar | ... | Raj Koothrappali (124 episodes, 2007-2013) |
| [6] | Melissa Rauch | ... | Bernadette Rostenkowski (54 episodes, 2009-2013) |
| [7] | Mayim Bialik | ... | Amy Farrah Fowler (52 episodes, 2010-2013) |
| [8] | Carol Ann Susi | ... | Mrs. Wolowitz (30 episodes, 2007-2013) |
| [9] | Kevin Sussman | ... | Stuart (21 episodes, 2009-2013) |
| [10] | Aarti Mann | ... | Priya Koothrappali / ... (12 episodes, 2010-2011) |
| [11] | Brian George | ... | Dr. Koothrappali / ... (9 episodes, 2007-2012) |
| [12] | Alice Amter | ... | Mrs. Koothrappali (9 episodes, 2007-2012) |
| [13] | Sara Gilbert | ... | Leslie Winkle (8 episodes, 2007-2010) |
| [14] | John Ross Bowie | ... | Barry Kripke / ... (8 episodes, 2009-2013) |
| [15] | Ian Scott Rudolph | ... | Captain Sweatpants (7 episodes, 2009-2013) |
| [16] | Wil Wheaton | ... | Wil Wheaton / ... (6 episodes, 2009-2013) |
| [17] | Mark Harelik | ... | Dr. Eric Gablehauser (5 episodes, 2007-2008) |
| [18] | Pasha D. Lychnikoff | ... | Dimitri (5 episodes, 2012) |
| [19] | Vernee Watson-Johnson | ... | Althea (5 episodes, 2007-2012) |
| [20] | Laurie Metcalf | ... | Mary Cooper (4 episodes, 2007-2013) |
| [21] | Brian Smith | ... | Zack (4 episodes, 2010-2011) |
| [22] | Robert Clotworthy | ... | Announcer / ... (4 episodes, 2008-2012) |
| [23] | Michael J. Massimino | ... | Himself (4 episodes, 2012) |
| [24] | Sara Rue | ... | Stephanie Barnett (3 episodes, 2008) |
| [25] | Brian Patrick Wade | ... | Kurt (3 episodes, 2007-2009) |
| [26] | Christine Baranski | ... | Beverly Hofstadter (3 episodes, 2009-2013) |
| [27] | Joshua Malina | ... | President Siebert (3 episodes, 2011-2012) |
| [28] | Margo Harshman | ... | Alex / ... (3 episodes, 2012-2013) |
| [29] | Casey Sander | ... | Mr. Rostenkowski / ... (3 episodes, 2012) |
| [30] | Owen Thayer | ... | Lonely Larry (3 episodes, 2009-2010) |
| [31] | James Hong | ... | Chen (2 episodes, 2007-2008) |
| [32] | Erin Allin O'Reilly | ... | Cheryl (2 episodes, 2007-2008) |
| [33] | Stephen Hawking | ... | Himself / ... (2 episodes, 2012) |
| [34] | Katee Sackhoff | ... | Herself / ... (2 episodes, 2009-2010) |
| [35] | LeVar Burton | ... | Himself (2 episodes, 2011-2012) |
| [36] | Kevin Brief | ... | Glen / ... (2 episodes, 2010-2012) |
| [37] | Edward Lieberman | ... | Announcer (2 episodes, 2010-2011) |
| [38] | Elena Campbell-Martinez | ... | Cleaning Lady / ... (2 episodes, 2008-2009) |
| [39] | Chris Krauser | ... | Club Patron (2 episodes, 2009) |
| [40] | Erin Pickett | ... |
Cafeteria Patron / ... (2 episodes, 2010) |
