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Dr. Boots Hofstadter is Leonard Hofstadter's childhood pet cat.

In "The 43 Peculiarity", Leonard asks Alex to call him "Leonard" because he feels "Dr. Hofstadter" refers to other members of his family. His mother (Beverly Hofstadter), father (Alfred Hofstadter), sister and the cat, which confuses Alex. Leonard adds that Dr. Boots Hofstadter's degree is probably honorary, which makes Alex laugh.

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