In the "Business Guy" episode of animated comedy Family Guy, Peter Griffin temporarily takes over his rich father-in-law's business empire and demotes Carter Pewterschnidt to janitor. He commands Pewter to throw a viewing party for the latest episode of The Big Bang Theory and to invite as many employees as possible to attend. But Carter discovers he is so universally loathed that nobody turns up.
A brief glimpse is given of TBBT in the Family Guy universe.
Sheldon Cooper is seen boasting that he can bench-press over 690 billion nanograms. Leonard objects that this is only two pounds of actual weight. As Penny looks on,Sheldon shrugs and says "it sounded way better the way I phrased it".
Johnny Galecki and Jim Parsons are credited with voicing their own characters. (Penny was silent).
Extract visible here.