The Cafeteria is a room at Caltech where Sheldon, Leonard, Raj and Howard often eat in, along with others. The cafeteria is seen in many episodes. Sometimes, significant events occur in the cafeteria, such as the introduction of Dennis Kim and the joining of Leslie Winkle to the Physics Bowl team of Leonard, Raj and Howard.

The Cafeteria contains a number of vending machines, including one that contains chocolate milk that attracted Dennis Kim. ("The Jerusalem Duality") There is also a 'COLD Drinks' machine, which is the same model as can be seen in the bowling alley in "The Wheaton Recurrence".

Penny and Amy spy on Sheldon and his new assistant Alex Jensen and see her flirting with Leonard in the cafeteria.