This woman is the wife of Wyatt's Father. She is the mother of Wyatt and mother-in-law of Susan. She is the paternal grandmother of Penny, Randall, as well as Penny And Randall's Sister. She is the ex-paternal grandmother-in-law of Zack Johnson and the current paternal grandmother-in-law of Leonard Hofstadter and Penny And Randall's Brother-in-law (Sister's Husband). She is a great-grandmother to Penny's Nephew. Penny And Randall's Cousin may be her possible grandson.

After Professor Proton asks Penny if she has any single grandmothers, Penny answers that they are both married.

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